VDK® Melatonin, World-First Bio-Fermented & Natural Melatonin

Home | Product | VDK® Melatonin

VDK® Melatonin

Chemical Name: N-Acetyl-5-methoxytryptamine

CAS Number: 73-31-4

Molecular Formula: C13H16N2O2

Structural Formula:

Core Production Process

Dual Technological Breakthroughs Worldwide, Setting a New Benchmark for Natural and Compliant Production

Compliant Process:

Compliant Process: Globally exclusive preparation of serotonin via bio-fermentation, followed by directional chemical synthesis in accordance with Chinese regulations, achieving 78% naturalness with full compliance standards.
Full Fermentation Process:

Full Fermentation Process: Based on breakthrough synthetic biology technology, VDK® Melatonin is produced through one-step fermentation using glucose as a carbon source, offering natural origin and representing a world-first innovation.
Dual Production Processes with Distinct Technological Recognition:

Dual Production Processes with Distinct Technological Recognition: VDK adopts green production pathways, resulting in a white-colored product, creating clear differentiation in terms of natural attributes, technological innovation, and compliance safety.

Exclusive Core Strengths

Qualifications Certification
Naturalness Report
Chromatogram
Quality Specifications
Differentiated Customization

Qualifications Certification:

VDK holds a Pharmaceutical Production License to meet the filing requirements of domestic end manufacturers. A series of certifications including ISO9001, ISO22000, HACCP, KOSHER, and HALAL together ensure standardized production and management of the product;

Quality Specifications:

VDK® Melatonin complies with both the national standard <Catalogue of Raw Materials for Health Foods – Melatoninand international pharmacopoeial standards including USP, BP, and EP. A full suite of compliance documentation, including factory inspection reports and third-party test certificates, is available upon request.

Regular Assay ≥99.5% Quality Specification：

Items	Regulatory quality standard	Fermented quality standard	Methods
Colour	White or Off-White	White or Off-White	Visual
State	Crystalline granule or Powder	Crystalline granule or Powder	Visual
Identification	HPLC	HPLC	HPLC
Identification	IR	IR	IR
Assay(On dry basis)	≥99.5%	≥99.5%	HPLC
5-Methoxytryptamine	≤0.1%	≤0.1%	HPLC
Loss On Drying	≤0.5%	≤0.5%	Technical Requirements2 for Melatonin Raw Materials
Residue On Ignition	≤0.1%	≤0.1%	Technical Requirements 3 for Melatonin Raw Materials
MAX Individual Impurities	≤0.1%	≤0.1%	HPLC
Total Impurities	≤1.0%	≤1.0%	HPLC
Lead(Pb)	≤2.0ppm	≤2.0ppm	ICP-MMS
Arsenic(As)	≤1.0ppm	≤1.0ppm	ICP-MMS
Mercury(Hg)	≤0.3ppm	≤0.3ppm	ICP-MS
Total Aerobic Bacteria	≤1000CFU/g	≤1000CFU/g	GB 4789.2
Yeast & Mold	≤100CFU/g	≤100CFU/g	GB 4789.15
Coliforms	≤0.92MPN/g	≤0.92MPN/g	GB 4789.3MPN
Salmonella	≤0/25g	≤0/25g	GB 4789.4
Staphylococcus	≤0/25g	≤0/25g	GB 4789.10
Biobased Carbon	78%	100%

10% Water Soluble Melatonin Quality Spedification:

Items	Specification	Methods
Appearance	White or Off-White Crystalline Powder	Visual
Identification	HPLC	HPLC
Water %	≤ 5.0%	CP2020<0832>
Water %	≤ 5.0%	CP2020<2302>
Heavy metals ppm	≤ 10ppm	CP2020<0821>
Lead(Pb)	≤ 2.0ppm	ICP-MS
Cadmium(Cd)	≤ 1.0ppm	ICP-MS
Arsenic(As)	≤ 1.0ppm	ICP-MS
Mercury(Hg)	≤ 0.1ppm	ICP-MS
Assay（On dry basis）	≥ 10%	HPLC
Total Aerobic Bacteria	≤ 1000CFU/g	GB 4789.2
Yeast & Mold	≤50 CFU/g	GB 4789.15
Coliforms	≤ 0.92 CFU/g	GB 4789.3MPN
Salmonella	Absent/25g	GB 4789.4
Staphylococcus	Absent/25g	GB 4789.10

Packaging Specifications:

25kg/drum (Inner packaging: double-layer PE bags; outer packaging: cardboard drum);
1kg/bag, 5kg/bag, 10kg/bag (Inner packaging: PE bags + aluminum foil bags; outer packaging: cartons);
Customized sub-packaging is available upon request. The product must be stored in light-proof and sealed conditions throughout the entire process.