
As global demand for sleep support supplements and functional health products continues to grow, sourcing high-quality melatonin powder has become a top priority for nutraceutical brands, pharmaceutical manufacturers, contract manufacturers, and bulk ingredient distributors. For procurement managers, R&D teams, and private label supplement companies, choosing the right melatonin API supplier directly impacts product efficacy, regulatory compliance, and long-term brand reputation.
In an increasingly competitive and regulated market, buyers are no longer looking for just competitive pricing—they require high purity standards, GMP-compliant production, stable supply chains, and complete technical documentation. Identifying reliable raw material manufacturers can be challenging, especially when quality consistency and international export experience vary significantly across suppliers.
This guide to the Top Melatonin Powder Manufacturers in the World 2026 highlights leading global producers specializing in bulk melatonin API. Whether you are developing a new sleep supplement line or securing long-term raw material partnerships, this list will help you evaluate reputable manufacturers capable of meeting international quality and regulatory requirements.

Establishment: 2010s
Headquarters: Taizhou, Zhejiang Province, China
Company Profile:
Conscientia Industrial Co., Ltd. is a leading Chinese manufacturer specializing in the research, development, and production of high-quality active pharmaceutical ingredients (APIs), nutritional ingredients, peptides, and fine chemicals for the global life sciences market. With deep expertise in bulk ingredient manufacturing, Conscientia serves pharmaceutical, nutraceutical, and supplement industries worldwide, offering an extensive portfolio of raw materials that includes melatonin API with high purity and consistent quality. The company’s products are manufactured to comply with international pharmacopeia standards such as USP and EP, making them suitable for use in dietary supplement formulations and industrial applications.
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Headquarters: China
Company Profile:
Blue Eyes Biotech is a China-based supplier specializing in the production and global distribution of high-purity melatonin powder and other nutritional raw materials. The company focuses on bulk active ingredients for the dietary supplement, nutraceutical, and pharmaceutical industries. Its melatonin API is widely supplied to international manufacturers seeking consistent purity, stable quality, and reliable large-scale sourcing. With an emphasis on standardized production processes and export-oriented service, Blue Eyes Bio supports global brands with compliant raw materials suitable for capsule, tablet, and functional food formulations.
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Headquarters: China
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Naturallifeworth is a prominent manufacturer and exporter of high-purity nutritional ingredients and active pharmaceutical raw materials, including melatonin powder. With a focus on serving the global dietary supplement and nutraceutical industries, Naturallifeworth offers standardized, quality-tested bulk ingredients that support formulation needs for sleep support, wellness, and functional health products. The company emphasizes strict quality control measures, on-time delivery, and comprehensive documentation to facilitate international compliance and supply chain transparency.
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Establishment: 1971
Headquarters: New Brunswick, New Jersey, USA
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Spectrum Chemical Mfg. Corp. is a well-established American manufacturer and distributor of fine chemicals, laboratory reagents, and active pharmaceutical ingredients, including melatonin powder in bulk quantities. With over five decades of experience serving regulated industries around the world, Spectrum Chemical offers a comprehensive catalog of USP, NF, FCC, BP, EP, and JP grade materials designed for research, pharmaceutical, nutraceutical, and industrial applications. The company’s capabilities include cGMP-compliant packaging and quality control testing in FDA-registered facilities, ensuring high-purity raw materials suitable for product development and large-scale manufacturing.
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Establishment: 1994
Headquarters: Hauppauge, New York, USA
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Rochem International Inc. is a U.S.-based manufacturer and distributor of pharmaceutical raw materials, fine chemicals, and active ingredients, including bulk melatonin powder for dietary supplement and research use. With decades of industry expertise, Rochem serves pharmaceutical, nutraceutical, cosmetic, and clinical research sectors with high-quality chemical ingredients sourced and manufactured under stringent quality controls. The company focuses on reliability, traceable supply chains, and comprehensive regulatory documentation to support global customers in formulation and production environments.
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The global melatonin powder market continues to expand as demand rises for high-quality sleep support and nutraceutical formulations. Choosing the right melatonin API manufacturer is critical for ensuring product purity, regulatory compliance, supply stability, and long-term brand credibility. The companies listed above represent some of the most recognized raw material producers in the world, offering bulk melatonin powder suitable for pharmaceutical and dietary supplement applications.
For brands seeking a reliable partner with strong technical expertise, strict quality control, and global supply capabilities, VDK NaturaSyn stands out as a trusted manufacturer of high-purity melatonin powder. With a commitment to consistent quality, professional documentation support, and scalable production capacity, VDK NaturaSyn is well-positioned to support supplement and pharmaceutical manufacturers worldwide in 2026 and beyond.